Viruses control cells in unexpected ways. They use a small number of proteins to redirect host pathways and cause large changes in the physiology of cells and organisms. In the Gaglia lab, we are interested in how virus-cell interactions play a role in the control and subversion of anti-viral innate immune responses, as innate immune responses have a crucial and dualistic role on outcome of infection. They can act as a barrier for the virus, reducing viral replication and disease. However, they can also cause dangerous tissue damage, especially if they are hyperactivated or misdirected.
We currently focus on virus-cell interactions in infections with the human respiratory virus influenza A virus and the human oncogenic virus Kaposi’s sarcoma associated herpesvirus (KSHV). By studying both RNA and DNA viruses, we have a unique vantage point to observe both conserved and individual mechanisms of host manipulation.
Our goal is to solve scientific puzzles and dig deeper to link molecular events during viral infections to human disease in a supportive environment that fosters learning and growth.
We recently relocated from Tufts University in Boston to UW-Madison and are excited to grow the team!
- Please check out our Open Positions page for positions we are actively recruiting for.
- Even if you do not see a posting, if you are interested in a position as a staff scientist, research assistant, postdoctoral fellow, or undergraduate intern, please contact Marta at Marta.Gaglia@wisc.edu.
- For undergraduates, also refer to our resources for undergraduate applicants page.
- If you are interested in doing a PhD, all admissions go through UW graduate programs. Marta is a trainer in the MDTP and CMB programs.